Chief is not optimized in any way for workstation cards and we don't put any additional emphasis on developing or testing for them relative to what we do for gaming cards. Generally speaking the hardware between workstation cards and gaming cards is very similar, but the drivers are optimized for very specific operations and often times explicitly for certain applications. Chief stands to gain very little, if anything, from these optimizations. The raw throughput that a gaming card is capable of is likely to be superior in the context of Chief. Both gaming cards and workstation cards implement OpenGL well.
There may be differences in the expected lifetime of the GPU and the support provided by the vendor for the workstation level cards, but I have little knowledge in this area.