BrownTiger,
Just wanted to follow-up that your fix worked. Changed the below line and it's writing the libraries to the D: now. Thanks again!
Manufacturer%20Data%20Path=D:/Program Files/Home Design/Home Designer Suite 2021/Manufacturer Data/
And Chopsaw, thanks for the advice. Yes, been there and done that, ALWAYS make backups now. Lesson learned the hard way...